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KMID : 0363220090470091098
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Korean Journal of Dermatology
2009 Volume.47 No. 9 p.1098 ~ p.1101
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Kang Min-Chul
Kim Sung-Ae
Lee Kyu-Suk
Cho Jae-We
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Abstract
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A 40-year-old male had a history of tinea pedis, which had been treated with itraconazole. One week later fever and pruritic, multiple, symmetric, erythematous papules developed, some of which became confluent, producing plaques on his face, trunk, and limbs. The skin biopsy showed subcorneal and spongiform pustules. One month later we had patch tests with itraconazole and other drugs. The result of the patch test using itraconazole was a (＋＋) reaction that showed erythematous macules, papulovesicles and patch (after 48 hours). So, we report here a rare case of acute generalized exanthematous pustulosis (AGEP) that manifests as generalized erythema, erythema multiforme and amicrobial pustules with fever due to itraconazole.
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KEYWORD
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Acute generalized exanthematous pustulosis, Itraconazole
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